Origin of the nucleus and Ran-dependent transport to safeguard ribosome biogenesis in a chimeric cell
Abstract Background The origin of the nucleus is a central problem about the origin of eukaryotes.The common ancestry of nuclear pore complexes (NPC) and vesicle coating complexes indicates that the nucleus evolved via the modification of a pre-existing endomembrane system.Such an autogenous scenario is cell biologically feasible, but it is not cle